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Table 2 Subgroup Analyses of POCUS and CXR diagnostic performance in detecting pleural effusion

From: Advancement in pleura effusion diagnosis: a systematic review and meta-analysis of point-of-care ultrasound versus radiographic thoracic imaging

Covariate

No. of studies

Sensitivity

Significance

Specificity

Significance

POCUS

 Sample size

  ≥ 100

1

93 (86.75–99.25)

0.64

96 (89.95–100)

0.54

  < 100

11

94.64 (91.66–97.61)

98.03 (95.76–100)

 Country

  United States

3

92.20 (84.18–100)

0.02

99.74 (97.68–100)

0.52

  Africa

3

97.60 (92.59–100)

98.09 (93.92–100)

  Asia

2

87.84 (82.94–92.74)

99.99 (95.86–100)

  Europe

5

96.46 (93.02–99.89)

95.86 (90.68–100)

 Level of POCUS training

  Experienced

10

94.44 (91.20–97.69

0.92

98.25 (96.54–99.97)

0.41

  Inexperienced

2

93.92 (84.54–100)

85.97 (56.64–100)

 Reference test

  CT scan

8

94.60 (90.73–98.47)

0.92

97.82 (95.56–100)

0.48

  Other

4

94.29 (89.74–98.84)

94.99 (87.45–100)

 Machine type

  Pocket-size

2

96.38 (90.60–100)

0.51

86.07 (56.75–100)

0.42

  Other

10

94.12 (90.80–97.45)

98.25 (96.53–99.97)

Chest X-ray

 Sample size

  ≥ 100

3

74.23 (61.22–87.25)

0.37

92.74 (85.41–100)

0.04

  < 100

12

65.82 (52.91–78.72)

80.98 (72.79–89.16)

 Country

  United States

3

70.40 (60.65–80.14)

0.87

83.04 (73.86–92.22)

0.97

  Africa

2

72.45 (64.36–80.55)

84.30 (66.98–100)

  Asia

2

62.89 (33.65–92.13)

88.11 (65.10–100)

  Europe

8

66 (47.70–84.30)

85.48 (77.59–93.36)

 Operator

  Radiologist

12

65.73 (52.85–78.61)

0.34

83.15 (76.33–89.98)

0.27

  Other

3

73.94 (63.26–84.63)

88.93 (81.24–96.62)

 Reference test

  CT scan

9

63.06 (53.93–72.19)

 < 0.001

87.79 (82.43–93.15)

 < 0.001

  CXR

2

93.38 (86.30–100)

98.51 (94.65–100)

  Other

4

65.28 (44.48–86.08)

67.76 (49.58–85.93)