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Table 1 Patient characteristics of patients referred to LH clinic for assessment for antiviral therapy of chronic hepatitis B

From: Point-of-care ultrasound to inform antiviral treatment initiation in chronic hepatitis B virus infection in low-resource settings – the PUSH protocol

 

Patients with ultrasound abnormalities (n = 31)

Patient without ultrasound abnormalities (n = 80)

 

Demographic

   

Sex (M/F, %)

25/6

(80.6%/19.4%)

47/33

(58.7%/41.2%)

p = 0.0309

Age, years [IQR]

35 [30–40]

30 [28–36]

 

Signs/symptoms

   

Abdominal swelling (%)

19 (61.3%)

5 (6.3%)

p < 0.0001

Abdominal pain (%)

18 (58.1%)

6 (7.5%)

p < 0.0001

Jaundice (%)

7 (22.6%)

8 (10.0%)

n.s.

Nausea/Vomiting (%)

11 (35.5%)

7 (8.8%)

p = 0.0007

Laboratory results

   

ALT (mean, 95% CI)

70 [50–91]

136 [57–214]

n.s.

AST (mean, 95% CI)

211 [117–305]

95 [43–146]

p = 0.024

Bilitot (mean, 95% CI)

3.6 [1.5–5.8]

2.6 [1.0-4.2]

n.s.

APRI# (mean, 95% CI)

5.0 [1.4–8.5]

1.6 [0.7–2.6]

p = 0.012

HBV Treatment

   

Treated

31 (100%)

14 (17.5%)

p < 0.0001

  1. #APRI Aspartase-aminotransferase (AST)-to-platelet ratio index calculated as (AST/AST-ULN) / platelet count x 100