Impaired cerebral autoregulation detected in early prevasospasm period is associated with unfavorable outcome after spontaneous subarachnoid hemorrhage: an observational prospective pilot study

The Ultrasound Journal

Table 3 Patient demographics and clinical examination data (patients with and without delayed cerebral ischemia and healthy control groups)

	DCI group	Non-DCI group	Healthy control	p (DCI, Non-DCI)	p (DCI, Cont.)	p (Non-DCI, Cont.)
Number	8	21	15	-	-	-
Age, years median [IQR]	68 [65–77]	65 [53–75]	37 [33–40]	0.59	< 0.001*	< 0.001*
Sex, M/F	4/4	12/9	12/3	0.76	-	-
GCS, IQR	[8–12]	[5–11]	-	0.35	-	-
CV, n	8	2	-	< 0.001*	-	-
∆T_CBFV, s mean (std)	1.57 (0.80)	2.05 (1.35)	2.76 (0.72)	0.73	0.002*	0.012*
Mx mean (std)	0.32 (0.16)	0.34 (0.23)	0.33 (0.08)	0.79	0.94	0.72
BRS_drop, ms/mmH mean (std)	1.14 (10.1)	-3.78 (7.34)	9.65 (6.86)	0.13	0.049*	< 0.001*
BRS _recovery, ms/mmHg mean (std)	-11.4 (6.79)	-5.65 (7.26)	-5.67 (4.94)	0.039*	0.032*	0.6

GCS is the Glasgow coma scale, CV is the cerebral vasospasm, DCI is the delayed cerebral ischemia, ∆T_CBFV is the time difference between cerebral blood flow velocity and arterial blood pressure, Mx is the mean flow autoregulation index, BRS_drop and BRS_recovery are the baroreflex sensitivity indices calculated as ratios between changes in interbeat interval and changes in arterial blood pressure (∆T_IBI/∆ABP) during the boot deflation cycle at falling and recovery moments, IQR is the interquartile range, std is the standard deviation, and Cont. is the control group. The asterisk (*) indicates statistical significance (p < 0.05)